Finasteride for transgender

Does finasteride increase estrogen?

Finasteride increases the circulating levels of testosterone which is peripherally aromatized to estrogens. Thus the use of finasteride in older males further shifts the hormonal balance towards estrogen excess. The expression of aromatase is also up-regulated in prostatic hyperplasia and cancer.

Does finasteride feminize?

However, unlike androgen receptor blockade with flutamide, finasteride did not totally abolish prostate differentiation or completely feminize the external genitalia, despite increasingly higher dose levels.

Can I take finasteride with testosterone?

Therefore, testosterone replacement can be safely prescribed alongside finasteride in patients with low testosterone (predominantly for general well being and bone strength) and benign prostatic hypertrophy.

What hormones do transgender males take?

Medications used in hormone therapy for transgender men include androgens and anabolic steroids like testosterone (by injection and other routes) to produce masculinization, suppress estrogen and progesterone levels, and prevent/reverse feminization; GnRH agonists and antagonists to suppress estrogen and progesterone …

Does finasteride cause shrinkage?

Finasteride, a hair-loss medication reportedly used by footballer Wayne Rooney, ‘could cause permanent impotence and shrink genitals in some men’ says the Daily Mail.

Does finasteride affect mood?

The author concluded that patients taking this medication may experience depressive symptoms and suicidal thoughts, and clinicians should advise patients of potential of the risk of adverse side effects.

Does Spiro increase estrogen?

Spironolactone has been found in some studies to increase levels of estradiol, an estrogen, although many other studies have found no changes in estradiol levels.

Does finasteride cause weight gain?

Hair growth that occurred while taking Propecia (finasteride) will be lost once you stop taking it. Does Propecia (finasteride) cause weight gain? Weight gain is not a known side effect of Propecia (finasteride).

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Does finasteride affect metabolism?

Prolonged treatment with finasteride (a 5 alpha-reductase inhibitor) does not affect bone density and metabolism.

Is finasteride hard on the kidneys?

However, as indicated by recent studies on androgen deprivation therapies (ADTs), it is possible that finasteride has an adverse effect on kidneys. A multiple cohort study with newly diagnosed non-metastatic prostate cancer showed that the use of ADT increased the risk of acute kidney injury (AKI) [6].16 мая 2019 г.

Does finasteride build muscle?

We conclude that a higher-than-replacement TE combined with finasteride significantly increases muscle strength and BMD and reduces body fat without causing prostate enlargement.

Does finasteride lower sperm count?

Some small differences have been seen in the semen of males taking finasteride, such as low sperm counts. For most men, their sperm levels returned to their normal levels when they stopped taking the medication. There are no reports linking this medication to infertility in humans or the inability to become pregnant.

How long does a transgender person have to take hormones?

The extent of these changes and the time interval for maximum change varies across patients and may take up to 18 to 24 months to occur. Use of anti-androgenic therapy as an adjunct helps to achieve maximum change. Hormone therapy improves transgender patients’ quality of life (20).

Does estrogen make a man feminine?

Traditionally, testosterone and estrogen have been considered to be male and female sex hormones, respectively. However, estradiol, the predominant form of estrogen, also plays a critical role in male sexual function. Estradiol in men is essential for modulating libido, erectile function, and spermatogenesis.

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